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Table 3 Percentage distribution of cell cycle stages in A549 cells treated with ALUP, BA, LUP

From: A novel lupene derivative from Thymus capitatus possesses an apoptosis-inducing effect via Let-7 miRNA/Cyclin D1/VEGF cascade in the A549 cell line

 

%G0-G1

%S

%G2/M

%Pre-G1

Control A549

44.62 ± 1.91

43.88 ± 1.88

11.5 ± 0.49

1.47 ± 0.06

ALUP

39.51 ± 1.69*#$

37.29 ± 1.6*#

23.2 ± 0.99*#$

16.89 ± 0.72*#

BA

28.79 ± 1.23*

33.67 ± 1.44*

37.54 ± 1.61*

25.72 ± 1.1*

LUP

33.75 ± 1.45*#

38.19 ± 1.64*#

28.06 ± 1.2*#

19.41 ± 0.83*#

  1. * Significance from A549 cells (untreated) at P < 0.0001
  2. # Significance from BA treatment at P < 0.001
  3. $ Significance from LUP treatment at P < 0.001