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Fig. 4 | BMC Complementary Medicine and Therapies

Fig. 4

From: A novel lupene derivative from Thymus capitatus possesses an apoptosis-inducing effect via Let-7 miRNA/Cyclin D1/VEGF cascade in the A549 cell line

Fig. 4

Real-time PCR analysis data depicting the relative normalized expression of let-7 miRNA, miRNA-21, Bax, CASP-8, CD95, KRAS, VEGF and Cyclin D1 after A549 treatment with ALUP, BA and LUP. P-values represented on the graph reflect the statistical significance of various treatments in comparison to untreated cells. The relative expression was calculate based on 2 − ΔΔCt method. * Significance from A549 cells (untreated) at P < 0.0001, # Significance from BA treatment at P < 0.001, $ Significance from LUP treatment at P < 0.01

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