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Table 5 Index of ADME properties to predict drug-likeliness of the ligands

From: The anticancer potential of chemical constituents of Moringa oleifera targeting CDK-2 inhibition in estrogen receptor positive breast cancer using in-silico and in vitro approches

Ligands

Mol. formula

Mol. Wt

g/mol

Rotatable

Bonds

H-bond

Acceptors

H-bond

Donors

Log Po/w

GI Absorption

Chlorogenic acid

C16H18O9

354.31

5

9

6

-0.39

Low

Quercetin

C15H10O7

302.23

1

7

5

1.23

High

Ellagic acid

C14H6O8

302.19

0

8

4

1.00

High

Niazirin

C14H17NO5

279.29

3

6

3

0.32

High

Kaempferol

C15H10O6

286.24

1

6

4

1.58

High

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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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