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Fig. 8 | BMC Complementary Medicine and Therapies

Fig. 8

From: Astragalus polysaccharide restores insulin secretion impaired by lipopolysaccharides through the protein kinase B /mammalian target of rapamycin/glucose transporter 2 pathway

Fig. 8

MK2206 and RPM inhibited the Akt/mTOR pathway. INS-1 cells were treated as indicated for 24 h. Untreated cells were included as a control. The levels of the indicated proteins were determined by western blot analysis. (A) Representative gel images. (B) Quantified protein ratios of p-Akt/t-Akt. (C) Quantified protein ratios of p-mTOR/t-mTOR. (D) Quantified GLUT2 protein expression. n = 3, *,#,ΔP < 0.05, **,##,ΔΔP < 0.01

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