The standardized extract of Centella asiatica L. Urb attenuates the convulsant effect induced by lithium/pilocarpine without affecting biochemical and haematological parameters in rats

Table 3 Complete haematic cytometry of rats treated with the vehicle, Centella asiatica or carbamazepine

Analyte	Vehicle (Purified Water)	Centella asiatica (200 mg/Kg)	Centella asiatica (400 mg/Kg)	Carbamazepine (300 mg/Kg)	Reference intervals*
MCHC	31.62 ± 0.26	31.86 ± 0.20	31.80 ± 0.18	31.24 ± 0.18	25.88–32.88 g/dl
Erythrocytes	8.65 ± 0.11	8.57 ± 0.02	8.52 ± 0.04	8.11 ± 0.10	7.8–8.65 mm³
Hto	43.09 ± 0.07	45.00 ± 0.00	44.44 ± 0.16	44.26 ± 1.02	35–45%
Hb	15.37 ± 0.61	16.89 ± 0.05	16.59 ± 0.24	16.27 ± 0.25	13.20–17.10 g/dl
MCH	18.26 ± 0.76	19.16 ± 0.22	18.37 ± 0.04	19.49 ± 0.23	15.53–20.05 pg
Leukocytes	12.13 ± 0.18	10.84 ± 0.69	12.64 ± 1.13	11.16 ± 0.57	4.0–17.0 mm³
Platelets	722.6 ± 54.28	645.3 ± 31.25	623.1 ± 22.65	717.7 ± 63.54	300.0-1500.0 mm³
MCV	56.43 ± 0.79	56.69 ± 0.87	53.57 ± 0.38	54.92 ± 0.72	45–65 fl.

Values are expressed as the mean ± SEM.*Source: Rivadeneyra et al., 2017 [50], 2018 [49]; Zamora-Bello et al., 2022 [51]

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