Fig. 1

The generation time of the first generalized seizure and epileptic status after the application of pilocarpine. A. First generalized seizure, comparison of groups: vehicle vs. Centella asiatica 200 mg/kg and 400 mg/kg by one-way ANOVA followed by Tukey’s post hoc test. B. SE induction, comparison of the groups: vehicle vs. Centella asiatica 200 mg/kg and 400 mg/kg by one-way ANOVA followed by Tukey’s post hoc test. C. Duration of the first generalized seizure. One-way ANOVA followed by Tukey’s post hoc test. Data are expressed as the mean ± SEM. * p < 0.05 vs. the vehicle group