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Table 4 Effects of BTL on kidney function markers of animals

From: Cytotoxicity, acute and sub-chronic toxicities of the leaves of Bauhinia thonningii (Schumach.) Milne-Redh. (Caesalpiniaceae)

Sexes

Studies animals, doses, and values of investigated parameters

 

Parameters

Doses of BTL and values of parameters

Control (0 mg/kg)

250 mg/kg

500 mg/kg

1000 mg/kg

Females

S-Crea (mg/dL)

0.84 ± 0.02a

0.83 ± 0.02a

0.85 ± 0.01a

0.97 ± 0.03b

S-Urea (mg/dL)

4.30 ± 0.42a

4.11 ± 0.37a

4.36 ± 0.33a

4.24 ± 0.40a

U-Crea (mg/dL)

212.03 ± 19.72ab

180.49 ± 14.40a

226.77 ± 23.32b

224.01 ± 22.79b

U-Proteins (g/dL)

0.04.03 ± 0.00a

0.03 ± 0.00a

0.04 ± 0.00a

0.04 ± 0.00a

U-Urea (mg/dL)

482.13 ± 30.37a

465.41 ± 30.93a

493.03 ± 26.84a

461.55 ± 21.38a

Males

S-Crea (mg/dL)

0.83 ± 0.02a

0.80 ± 0.05a

0.80 ± 0.07a

0.79 ± 0.08a

S-Urea (mg/dL)

3.62 ± 0.43ab

3.97 ± 0.13b

3.22 ± 0.45a

3.85 ± 0.35ab

U-Crea (mg/dL)

257.10 ± 37.69a

246.09 ± 28.48a

255.03 ± 27.55a

248.12 ± 7.66a

U-Proteins (g/dL)

0.04 ± 0.00ab

0.05 ± 0.00ab

0.04 ± 0.00a

0.06 ± 0.00b

U-Urea (mg/dL)

451.08 ± 78.88a

501.25 ± 46.65a

439.74 ± 25.76a

496.46 ± 74.50a

  1. Data are expressed as mean ± SD, n = 4. Values for a given group in a column followed by a different letter as a superscript are significantly different (p < 0.05). S-Crea serum creatinine, U-Crea urine creatinine, S-Urea serum urea, U-Urea urine urea, U-Proteins urine proteins