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Table 3 Effect of BTL on hematological parameters of animals

From: Cytotoxicity, acute and sub-chronic toxicities of the leaves of Bauhinia thonningii (Schumach.) Milne-Redh. (Caesalpiniaceae)

Sexes

Studies animals, doses, and values of investigated parameters

 

Parameters

Doses of BTL and values of parameters

  

Control (0 mg/kg)

250 mg/kg

500 mg/kg

1000 mg/kg

Females

WBC (103/ml)

8.68 ± 1.79a

7.96 ± 0.89a

7.50 ± 1.62a

7.60 ± 1.41a

RBC (106/mL)

7.92 ± 0.19a

8.09 ± 0.27a

8.34 ± 0.20a

8.07 ± 0.24a

Hb (g/dL)

13.87 ± 0.33a

13.48 ± 0.73a

14.23 ± 0.26a

14.50 ± 0.37a

HCT (%)

40.52 ± 1.47a

41.65 ± 0.21a

41.86 ± 0.66ab

41.87 ± 1.47ab

PLT (103/mL)

600.83 ± 11.30a

588.16 ± 16.57a

599.66 ± 11.94a

602.00 ± 14.13a

LYM (%)

58.85 ± 4.84a

60.18 ± 0.59a

54.00 ± 6.64a

56.35 ± 3.17a

MID (%)

8.75 ± 0.73a

8.00 ± 1.97a

7.20 ± 1.13a

8.05 ± 1.40a

GRAN%

31.82 ± 4.68a

33.38 ± 0.82a

34.12 ± 1.81a

32.97 ± 5.98a

Males

WBC (103/ml)

9.92 ± 0.47a

9.30 ± 4.08a

8.86 ± 4.10a

10.50 ± 1.98a

RBC (106/mL)

8.44 ± 0.61a

8.08 ± 0.41a

8.33 ± 0.28a

7.94 ± 0.70a

Hb (g/dL)

14.66 ± 0.68a

13.85 ± 0.36a

14.84 ± 0.44a

13.47 ± 1.55a

HCT (%)

42.12 ± 1.91a

40.15 ± 1.80a

42.62 ± 2.10a

40.53 ± 2.18a

PLT (103/mL)

667.75 ± 82.77ab

568.75 ± 49.64a

704.25 ± 98.58b

632.00 ± 19.20ab

LYM (%)

53.37 ± 3.01a

54.48 ± 3.70a

54.77 ± 5.61a

55.83 ± 1.65a

MID (%)

9.45 ± 0.50a

9.55 ± 1.72a

9.22 ± 0.98a

10.95 ± 1.49a

GRAN%

32.53 ± 2.52a

34.05 ± 2.18a

32.11 ± 1.65a

32.88 ± 3.05a

  1. Data are expressed as mean ± SD, n = 4. Values for a given group in a line followed by a different letter as a superscript are significantly different (P < 0.05). RBC red blood cells, Hb hemoglobin, LYM lymphocytes, MID mean corpuscular volume, GRAN granulocytes, WBC white blood cells, PLT platelets, HCT hematocrit