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Fig. 8 | BMC Complementary Medicine and Therapies

Fig. 8

From: Milk thistle nano-micelle formulation promotes cell cycle arrest and apoptosis in hepatocellular carcinoma cells through modulating miR-155-3p /SOCS2 /PHLDA1 signaling axis

Fig. 8

Cellular apoptosis analysis N-MT-treated Huh-7 cells. Huh-7 cells were treated by 2 and 1.5 µg/mL nano missile encapsulated milk thistle, and then, the apoptotic population was measured by the Annexin V-PI assay, using flow cytometry at 24h and 48h. A Flow cytometry of the apoptosis for untreated cells,(B, C) Flow cytometry of the apoptosis for N-MT-treated Huh-7 cells at two different time points (24h and 48h) after treatment, and (D) Apoptotic cell percentage of total cells was increased at 24h, and 48h in Huh-7 cell line. ∗  ∗ P < 0.01, ∗  ∗  ∗ P < 0.001

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