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Fig. 7 | BMC Complementary Medicine and Therapies

Fig. 7

From: Milk thistle nano-micelle formulation promotes cell cycle arrest and apoptosis in hepatocellular carcinoma cells through modulating miR-155-3p /SOCS2 /PHLDA1 signaling axis

Fig. 7

Effect of N-MT on cell cycle in HepG2 cells, using flow cytometry. HepG2 cells were treated with 2.3 and 3.1 µg/mL nano missile encapsulated milk thistle at 24h and 48h, respectively. Panel (A) Shows the population of untreated cells in Sub-G1/G1, S and G2/M stages. Panel (B, C) Show the population of N-MT-treated HepG2 cells in Sub-G1/G1, S and G2/M stages at two different time points (24h and 48h) after treatment. Panel (D) Represents the percentage of the HepG2 cells in sub-G1/G1 stage after 24h and 48h treatment compared to the control group. Sub-G1/G1 cell proportion has increased due to the effect of N-MT in a time-dependent manner. ∗ P < 0.05, ∗  ∗ P < 0.01

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