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Table 2 Quantitation of apoptotic genes expression after 24 and 96 h of cell exposure (Caspase, Bax and anti-apoptotic BCl2) on a transcriptional level

From: HPLC-ESI/MS-MS characterization of compounds in Dolomiaea costus extract and evaluation of cytotoxic and antiviral properties: molecular mechanisms underlying apoptosis-inducing effect on breast cancer

Treatment

Caspase 3

RQ 2−∆∆CT

Bcl2

RQ 2−∆∆CT

Bax

RQ 2−∆∆CT

24 h

96 h

24

96 h

24 h

96 h

Cell control

1

1

1

1

1

1

D. Costus

13.1

822

1.8

824

2.1

213

Paclitaxel

17.3

325

2.4

44.9

5

164.2

  1. IF RQ < 1 it is down regulation, > 1 up-regulation
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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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