Fig. 9

TEM images of MC3T3-E1 cells cultured in the following medium on day 7. a negative control (culture medium); (b) an enlargement of the images of (a). c 500 μg/ml Uncaria gambir extract; (d) an enlargement of the images of (c). e MTA eluate with 48 h setting time; (f) an enlargement of the images of (e). The white bar represents 2 μm (magnification x4000); the yellow bar represents 1 μm (magnification x6000). N: nucleus, R: rough endoplasmic reticulum, M: mitochondria, swollen mitochondria (red arrow), autolysosomes and autophagic vesicles (red arrowhead)