Endophytic fungal species Nigrospora oryzae and Alternaria alternata exhibit antimicrobial activity against gram-positive and gram-negative multi-drug resistant clinical bacterial isolates

Table 4 Antimicrobial activities exhibited by Fractions from bioactive fungal endophytes whole broth against at least one of the tested microorganisms; S. aureus ATCC 25923, S. aureus CS, MRSA 25775, and MDR Pseudomonas 2625374

Bacterial ID	Fungal endophytes crude extract fractions Zone of inhibition diameter (mm)
	*A. Alternaria* P02PL2						*A. alternaria* P02MS1						*N. oryzae* P02MS2A
	FA	FB	FC	FD	FE	Fungi-free extract	FA	FB	FC	FD	FE	Fungi-free extract	FA	FB	FC	FD	FE	Fungi-free extract
S . *aureus* ATCC 25923	-	8	-	-	11	-	-	12	13	-	-	-	-	9	-	-	-	-
*S. aureus* CS	-	9	-	-	-	-	-	9	9	-	-	-	-	8	-	-	-	-
MRSA 25775	-	8	-	-	-	-	-	9	8	-	-	-	-	9	-	-	-	-
MDR *Pseudomonas* 5625574	-	8	9	-	-	-	-	8	9	-	-	-	-	9	-	-	-	-

FA − E Fractions A to E, (−) No activity, ATCC American Type Culture Collection, CS Clinical Strain, MRSA Methicillin Resistant Staphylococcus aureus, MDR Multidrug resistant

ISSN: 2662-7671