Endophytic fungal species Nigrospora oryzae and Alternaria alternata exhibit antimicrobial activity against gram-positive and gram-negative multi-drug resistant clinical bacterial isolates

Table 3 Minimum inhibitory concentrations shown by fungal endophytes whole broth extracts, Ciprofloxacin as positive control, and fungi-free extract as negative control. All fungal endophytes whole broth extracts were tested in duplicates and mean MICs were calculated

Fungal endophytes	Tested bacteria strains, mean MICs (μg/mL)
Fungal endophytes	*S. aureus* ATCC 25923	*S. aureus* C. S	MRSA 5627679	MDR *Pseudomonas* 5625574
A. alternata P02PL2	32	64	32	256
A. alternata P02MS1	64	64	128	64
N. oryzae P02MS2A	32	32	1	16
Ciprofloxacin	-	-	-	-
Fungi-free extract	-	-	-	-

ATCC Amerlfoxideican Type Culture Collection, CS Clinical Strain, MRSA Methicillin Resistant Staphylococcus aureus, MDR Multidrug resistant; (−): no activity, MICs Minimum inhibitory concentrations

ISSN: 2662-7671