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Table 2 Antibacterial activities of whole broth extract of endophytic fungal isolates. Whole broth extracts of A. alternata P02PL2, A. alternata P02MS1, and N. oryzae P02MS2A were tested against S. aureus ATCC 25923 (A), S. aureus C.S (B), MRSA (methicillin-resistant S. aureus) 25775 (C), and MDR (multidrug-resistant) Pseudomonas (D). The control included a fungi-free MEB whole broth extract), and the diluent, 0.2% dimethyl sulfoxide (DMSO). The Zone of inhibition sizes represents the mean values of triplicates from each fungal whole broth extract

From: Endophytic fungal species Nigrospora oryzae and Alternaria alternata exhibit antimicrobial activity against gram-positive and gram-negative multi-drug resistant clinical bacterial isolates

Bacterial ID

Zone of inhibition diameter (mm)

Fungal extracts bioactivities

Experimental controls

A. alternata P02PL2 extracts

A. alternata P02MS1 extract

N . oryzae P02MS2A extract

Fungi-free extracts

0.2% DMSO

S .  aureus  ATCC 25923

14 ± 0.8

13.7 ± 0.9

10.7 ± 0.5

-

-

S. aureus  CS

9.7 ± 0.5

10.3 ± 0.9

11

-

-

Carbapenem-resistant A. baumanii (CRAB) 5630942

-

-

-

-

-

Multidrug-resistant (MDR) A. baumanii 5630947

-

-

-

-

-

Vancomycin-resistant Enterococcus (VRE) 05114870

-

-

-

-

-

MRSA 25775

11 ± 0.5

11.3 ± 1.2

9.7 ± 0.5

-

-

MDR  Pseudomonas  5625574

10.7 ± 0.5

9.7 ± 1.2

13.7 ± 1.7

-

-

  1. ATCC Amerlfoxideican Type Culture Collection,CS Clinical Strain, MRSA Methicillin Resistant Staphylococcus aureus, MDR Multidrug resistant, DMSO Dimethyl sulfoxide, (−) No activity