Fig. 3

Morphological aspects of the cell lines after 24-h treatment with compound 1. Cells were treated with different concentrations of Compound 1. A – A549 cells without treatment. B-D – A549 cells treated with compound 1 in the concentrations of 1.1, 2.2 and 4.4 µM respectively. E – B16-F10 cells without treatment. F–H – B16-F10 cells treated with compound 1 in the concentrations of 0.75, 1.5 and 3 µM respectively. I – C6 cells without treatment. J-L – C6 cells treated with compound 1 in the concentrations of 1.1, 2.2 and 4.4 µM respectively. Solid arrow indicates the position of apoptotic cells and dotted arrows indicate the position of cells with reduced cytoplasm. Bar—50 µm. Representation of two independent experiments