Fig. 1
Evaluation of selected crude extracts from Prabchompoothaweep remedy in experimental cerebral malaria (ECM) model. C57BL/6 mice are inoculated with 1 × 107 P. berghei ANKA and treated with artesunate, crude extract from Prabchompoothaweep remedy, or 7% Tween 80 from day 6 to day 12 post-infection. A The parasitemia levels are evaluated through thin blood smear film from the vascular tail vein beginning on days 3, 4, 5, 6, 7, 8, 10, and 12. Parasitemia levels are calculated from the number of parasitized red blood cells in at least 300 red blood cells. B Clinical score of mice at days 0, 4, 6, 8, 10, and 12 post-infection. C Body weight variation of mice during infection. ECM, experimental cerebral malaria; RMCBS, Rapid murine coma and behavior score; PbA, Plasmodium berghei ANKA,;Art, artesunate; AL, A. lancea; PT, Prabchompoothaweep remedy. Results are shown as mean ± standard error of the mean (SEM) (n = 5 per group). * p < 0.05 vs. PbA, ** p < 0.001 vs. PbA