Fig. 1From: Combination of bioaffinity ultrafiltration-UFLC-ESI-Q/TOF-MS/MS, in silico docking and multiple complex networks to explore antitumor mechanism of topoisomerase I inhibitors from Artemisiae Scopariae HerbaASH extract promotes viability deficiency and apoptosis of A549 cells. a, Cytotoxicity of ASH extract to A549 cells by SRB assay. Cells were treated with ASH extract for 48Â h, and that quercetin was used as positive control. b, Nuclear morphological changes by Hoechst 33,342 staining. The phase contrast (top) and fluorescence (bottom) images were collected using fluorescence microscopyBack to article page