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Table 1 Combination index (CI) and dose reduction index (DRI) values for Amy and Sor combinations in HepG2 cells

From: Hepatocellular Carcinoma cells: activity of Amygdalin and Sorafenib in Targeting AMPK /mTOR and BCL-2 for anti-angiogenesis and apoptosis cell death

Cell line

Dose

DRI50

CI50

Interpretation

HepG2

Amygdalin: 2.04 mg/ml

1.8

0.56

Strong Synergism

Sorafenib: 0.74 µM

43.5

  1. CI50 is the combination index for the 50% effect