Fig. 3

Effects of MLE treatment on hyperglycemia. A Fasting blood glucose. B Glycated hemoglobin (HbA1c). C Fasting insulin. D HOMA-IR. E Oral glucose tolerance test (OGTT). F AUC of OGTT. G Insulin resistance test (ITT). H AUC of ITT. Data were shown as mean ± SD (n = 9). *P < 0.05, **P < 0.01 vs. normal group; #P < 0.05, ##P < 0.01 vs. T2DM group. T2DM Type 2 diabetes mellitus, MLE Mulberry leaf extract. Week 0 = week of treatment, the first day of week 0 is the day of treatment. Note that the color of the * and # indicating significance match the color of the respective group