The aqueous extract of Artemisia Absinthium L. stimulates HO-1/MT-1/Cyp450 signaling pathway via oxidative stress regulation induced by aluminium oxide nanoparticles (α and γ) animal model

Table 3 Body weight, liver weight and relative weight changes of the rats from control, Al₂O₃ (γ and α) and Abs supplemented groups

Group	Initial weight(g)	Final weight (g)	Body gain(g)	Gain relative weight	Liver weight(g)	Liver relative weight
Control	213.5 ± 17.77	246.5 ± 21.22	33 ± 6.29	13.34 ± 1,93	12.45 ± 1.16	5.05 ± 0.29
Abs	202 ± 9.59	224.5 ± 9	22.5 ± 9.93	9.95 ± 4.23	11.02 ± 1.18	4.89 ± 0.35
γ -Al₂O₃	192 ± 15.93	202.33 ± 22.28	10.33 ± 4.36^a	4.77 ± 4.95^b	8.47 ± 1.53^a	4.17 ± 0.47^b
γ-Al₂O₃ + Abs	198.67 ± 16.7	216 ± 17.45	17.33 ± 4.13^c	8.02 ± 1.78	9.98 ± 1.52	4.61 ± 0.45
α-Al₂O₃	196.83 ± 17.8	214.83 ± 23.2	18 ± 8.22^c	8.22 ± 2.89	9.52 ± 1.7^c	4.41 ± 0.51
α-Al₂O₃ + Abs	186 ± 17.16	207.4 ± 17.7	21.4 ± 9.71	10.09 ± 4.31	9.83 ± 1.14^c	4.71 ± 0.30

The presented data represent the mean ± standard deviation. Mean initial, final body weight, body gain, gain relative weight, liver weight and liver relative weight: P value was considered significant at ^aP ≤ 0.001, ^bP ≤ 0.01, and ^cP ≤ 0.05 compare to control (One-way ANOVA)

ISSN: 2662-7671