Table 1 The results of SIN-core targets molecular docking
Protein name | Vina | Cavity | Center | Size | ||||
|---|---|---|---|---|---|---|---|---|
| Â | score | size | x | y | z | x | y | z |
TNF | -6.2 | 1281 | 38 | 18 | 46 | 27 | 19 | 19 |
IL1B | -5.9 | 78 | 3 | -14 | 15 | 19 | 19 | 19 |
IL6 | -7 | 533 | -20 | 17 | 27 | 19 | 19 | 19 |
STAT3 | -6.7 | 1726 | 106 | 55 | 131 | 19 | 27 | 19 |
MMP9 | -7.3 | 895 | 19 | 31 | 0 | 19 | 19 | 19 |
CXCL8 | -7.1 | 1468 | -24 | -21 | 20 | 19 | 35 | 19 |
PTGS2 | -7.8 | 4378 | 62 | 50 | 79 | 26 | 29 | 26 |
JAK2 | -7.9 | 2168 | 248 | -57 | 37 | 30 | 19 | 19 |
IL18 | -6.9 | 2706 | -7 | 81 | 117 | 31 | 19 | 26 |
NFKB1 | -5.7 | 46 | 38 | 32 | 5 | 19 | 19 | 19 |