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Table 1 Summary of the included studies

From: Clinical effects of cognitive behavioral therapy in heart failure patients: a meta-analysis of randomized controlled trials

Study ID

Study registration

Sample Size

Setting

Inclusion criteria

Number of CBT sessions

Control

Primary outcomes

Follow up

Cajanding et al. 2016

 N/R

100

Philippines

(1) Adults hospitalized patients with HF

(2) Not for other co-morbidities.

Once weekly for 12 weeks

Usual care

Quality of life, self-esteem, and mood scores

13 weeks

Dekker et al. 2012

NCT01275742

42

USA

(1) Patients with 21 years or older admitted with HF at 2 Lexington, Kentucky, hospitals (2) Patients with preserved or non-preserved systolic HF were eligible.

A single, 30-minute, one-on-one session

Usual care

Depressive symptoms

13 weeks

Freedland et al. 2015

NCT01028625

158

USA

(1) Patients diagnosed with HF 3 months or less before the screening

(2) Current severe depressive episode, and a “depressed” Beck Depression Inventory score (BDI-II) (≥ 14).

Once weekly for 12 weeks up to 6 months

Usual care

Severity of depression

26 weeks

Freedland et al. 2022

NCT02997865

139

USA

(1) Medically treated patients had a New York Heart Association class I-III HF diagnosis.

For the first eight weeks, sessions were conducted every week.

Usual care

Severity of depression

32 weeks

Hwang et al. 2022

NCT01937936

26

USA

(1) Patients had to be over the age of 21.

(2) Patients with a primary or secondary diagnosis of HF NYHA class II-IV)

(3) Patients with a family member providing care at home and be able to converse in English.

Once weekly for eight weeks

General Health Education

Salivary cortisol

26 weeks

Khayati et al. 2020

IRCT20160924029954N9

80

Iran

(1) Patients with heart failure who had been hospitalized.

(2) Detection of heart failure based on patient data

(3) BDI score of at least 21, depression diagnosis based on MSE by clinical psychologist

Five sessions

Conventional training

Depressive symptoms and severity of depression

8 weeks

Moradi et al. 2022

 N/R

66

Iran

(1) According to the AHA, inclusion criteria included age range of 45–70 years, fluency in the Persian language, and stage B or higher heart failure.

Three times a week for 3 weeks

To comply with ethical standards, control group patients had 4 online CBT training sessions.

Death anxiety and depression

4 weeks

  1. CBT: Cognitive Behavioral Therapy, NYHA: New York Heart Association, HF: Heart Failure, AHA: American Heart Association, PDI: Beck Depression Inventory, MSE: Mental Status Examination, N/R: not reported