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Table 2 Quorum sensing inhibition zones in C. violaceum CV026 by compounds

From: Evaluation of anti-quorum sensing and antibiofilm effects of secondary metabolites from Gambeya lacourtiana (De Wild) Aubr. & Pellegr against selected pathogens

Compound

Anti-quorum sensing inhibition zones (mm)

MIC (mg/mL)

MIC

MIC/2

MIC/4

Acetylerythrodiol

0.50

12.0 ± 1.0

9.1 ± 0.4

-

Amyrincapraote

1.00

9.1 ± 0.5

-

-

Erythrodiol 3-O-palmitate

1.00

7.5 ± 0.2

-

-

Erythrodiol

> 1.00

-

-

-

3-O-acetylbetulin

0.50

11.5 ± 0.5

-

-

Betulinic acid

1.00

11.0 ± 0.2

8.5 ± 0.2

-

3-O-acetyllupeol

1.00

9.0 ± 0.5

-

-

Lupeol

1.00

-

-

-

Myrianthic acid

0.50

12.0 ± 1.0

9.8 ± 0.4

-

Pomolic acid

0.50

13.0 ± 0.5

10.5 ± 0.7

-

Ursolic acid

1.00

14.0 ± 1.0

11.3 ± 0.5

-

Taraxerone

1.00

-

-

-

22,23-Dihydrospinasterol 3-O-β-D-glucopyranoside

> 1.00

-

-

-

Spinasterol

> 1.00

-

-

-

Spinasterol 3-O-β-D-glucopyranoside

> 1.00

-

-

-

Stigmasterol

> 1.00

-

-

-

Lacourtianamide

0.50

13.5 ± 0.5

9.1 ± 0.5

-

Lacourtianoside II

> 1.00

-

-

-

Epicatechin

0.50

16.0 ± 1.0

11.5 ± 0.5

9.5 ± 0.1

Methyl pheophorbide-a

1.00

13.0 ± 1.0

10.3 ± 0.1

-

  1. -: No inhibition; values are means ± SEM for three parallel measurements