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Table 1 Inhibition of violacein production in C. violaceum CV12472 by compounds

From: Evaluation of anti-quorum sensing and antibiofilm effects of secondary metabolites from Gambeya lacourtiana (De Wild) Aubr. & Pellegr against selected pathogens

Compound

MIC (mg/mL)

Violacein inhibition (%)

MIC

MIC/2

MIC/4

MIC/8

Acetylerythrodiol

1.00

45.5 ± 1.5

26.0 ± 0.6

14.2 ± 0.28

-

Amyrincapraote

0.50

29.3 ± 0.2

10.5 ± 0.1

-

-

Erythrodiol 3-O-palmitate

0.50

18.5 ± 0.5

07.9 ± 0.3

-

-

Erythrodiol

1.00

37.3 ± 0.8

13.6 ± 0.1

-

-

3-O-acetylbetulin

1.00

60.1 ± 1.0

21.9 ± 0.6

-

-

Betulinic acid

0.50

26.9 ± 0.1

15.1 ± 0.4

-

-

3-O-acetyllupeol

1.00

27.5 ± 1.1

10.0 ± 0.5

-

-

Lupeol

1.00

38.0 ± 0.4

12.9 ± 0.2

-

-

Myrianthic acid

1.00

25.8 ± 0.7

10.3 ± 0.4

-

-

Pomolic acid

0.50

44.2 ± 0.22

28.0 ± 0.5

9.7 ± 0.2

-

Ursolic acid

1.00

60.1 ± 1.0

21.9 ± 0.6

7.5 ± 0.4

-

Taraxerone

0.50

25.9 ± 0.6

11.0 ± 0.3

-

-

22,23-Dihydrospinasterol 3-O-β-D-glucopyranoside

1.00

20.5 ± 0.3

-

-

-

Spinasterol

1.00

20.9 ± 0.10

11.3 ± 0.5

-

-

Spinasterol 3-O-β-D-glucopyranoside

1.00

17.49 ± 0.6

-

-

-

Stigmasterol

1.00

22.9 ± 0.8

06.7 ± 0.2

-

-

Lacourtianamide

0.50

43.8 ± 1.5

19.7 ± 0.4

5.5 ± 0.1

-

Lacourtianoside II

> 1.00

-

-

-

-

Epicatechin

0.25

100 ± 0.00

86.7 ± 1.7

39.8 ± 0.6

17.2 ± 0.9

Methyl pheophorbide-a

0.50

41.0 ± 1.0

22.6 ± 0.5

8.4 ± 0.5

-

  1. -: No inhibition; values are means ± SEM for three parallel measurements