Fig. 3From: Jatrophone: a cytotoxic macrocylic diterpene targeting PI3K/AKT/NF-κB pathway, inducing apoptosis and autophagy in resistant breast cancer cellsEvaluation of cell death modality (Apoptosis/necrosis) in resistant breast cancer cells (MCF-7ADR cells) after jatrophone treatment for 48 h followed by double staining with Annexin-FITC/PI. (A) Quantification of cells in different stages; (B) Different cell populations of early apoptosis, late apoptosis, and necrosis with total cell death were plotted as a percentage of total events. Data are presented as mean ± SD; n = 3. * Statistically significant from controlBack to article page