Fig. 1

PQS+DAPT further decreased platelet aggregation, attenuated MI expansion and cardiac injury in AMI rats. A ADP-induced MPAR measured by light transmission aggregometry revealed potentiated inhibition of platelet aggregation by PQS+DAPT compared with DAPT. Each dot represents one rat (n = 12). B MI expansion was visualized by TTC staining and infarct size was measured using Image J software. PQS+DAPT further diminished infarct size relative to DAPT. Each dot represents one rat (n = 10). C Representative images of TTC staining. D Representative images of myocardial histopathology by H&E staining (× 100, Scale bar: 200 μm; × 200, Scale bar: 100 μm). Multiple group comparison was conducted by one-way ANOVA. *P < 0.05, **P < 0.01. Data were mean ± SEM in all panels