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Fig. 4 | BMC Complementary Medicine and Therapies

Fig. 4

From: Fumigaclavine C ameliorates liver steatosis by attenuating hepatic de novo lipogenesis via modulation of the RhoA/ROCK signaling pathway

Fig. 4

FC ameliorates liver injury without significant adverse side effects in HFD-induced obese mice. A-E The levels of serum TG A, TC B, LDL-c C, HDL-c D, and FFA E were measured. F–H Liver injury was evaluated via serum T-bili F, ALT G, and AST H levels. Adverse side effects of FC were examined via serum creatinine I and creatine kinase J. TG, Triglyceride; TC, total cholesterol; LDL-c, low density lipoprotein-cholesterol; HDL-c, high density lipoprotein-cholesterol; FFA, free fatty acid; T-bili, total bilirubin; ALT, alanine transaminase; AST, aspartate transaminase. Sim (40 mg/kg) acted as the positive control group. Each value represents as means ± S.E.M. of triplicate experiments. # P < 0.01 as compared with the control group. * P < 0.05, ** P < 0.01, and *** P < 0.001 as compared with the HFD-induced group

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