Table 3 Vina scores and cavity information of the hub targeted proteins
From: The potential effect and mechanism of Saikosaponin A against gastric cancer
No | Receptor | PDB ID | Binding sites with the amino acid | Autodock score (kcal/mol) |
|---|---|---|---|---|
1 | STAT3 | 6QHD | GLU-324, LYS-348, ASN-400 | -7.9 |
2 | MYC | 1EE4 | ALA-937, LYS-939, LYS-918 | -7.6 |
3 | TNF | 5MU8 | LEU-26, GLU-135, ASP-45, GLN-47, LSY-90 | -7.5 |
4 | STAT5B | 6MBW | SER-463, ARG-493, GLU-490, PRO-491 | -9.2 |
5 | CASP3 | 6X8I | ASN-73, GLN-217, LYS-242 | -9.2 |
6 | SRC | 6E6E | GLU-527, GLN-531 | -8.4 |