Table 1 Potential common targets for SSA in the treatment of GC
From: The potential effect and mechanism of Saikosaponin A against gastric cancer
No | Uniport ID | Gene | Protein names |
|---|---|---|---|
1 | Q07812 | BAX | Apoptosis regulator BAX |
2 | P10415 | BCL2 | Apoptosis regulator Bcl-2 |
3 | P51692 | STAT5B | Signal transducer and activator of transcription 5B |
4 | P06239 | LCK | Tyrosine-protein kinase Lck |
5 | P10721 | KIT | Mast/stem cell growth factor receptor Kit |
6 | P00519 | ABL1 | Tyrosine-protein kinase ABL1 |
7 | P19838 | NFKB1 | Nuclear factor NF-kappa-B p105 subunit |
8 | P40763 | STAT3 | Signal transducer and activator of transcription 3 |
9 | P29317 | EPHA2 | Ephrin type-A receptor 2 |
10 | P01106 | MYC | Myc proto-oncogene protein |
11 | P24941 | CDK2 | Cyclin-dependent kinase 2 |
12 | P11387 | TOP1 | DNA topoisomerase 1 |
13 | Q9UKK6 | NXT1 | NTF2-related export protein 1 |
14 | P06241 | FYN | Tyrosine-protein kinase Fyn |
15 | P04629 | NTRK1 | High affinity nerve growth factor receptor |
16 | Q08345 | DDR1 | Epithelial discoidin domain-containing receptor 1 |
17 | P42574 | CASP3 | Caspase-3 |
18 | P01375 | TNF | Tumor necrosis factor |
19 | P07947 | YES1 | Tyrosine-protein kinase Yes |
20 | P12931 | SRC | Proto-oncogene tyrosine-protein kinase Src |
21 | P09619 | PDGFRB | Platelet-derived growth factor receptor beta |
22 | P23219 | PTGS1 | Prostaglandin G/H synthase 1 |
23 | P06400 | RB1 | Retinoblastoma-associated protein |
24 | P05113 | IL5 | Interleukin-5 |
25 | P16234 | PDGFRA | Platelet-derived growth factor receptor alpha |
26 | P12724 | RNASE3 | Eosinophil cationic protein |
27 | P43115 | PTGER3 | Prostaglandin E2 receptor EP3 subtype |
28 | P60568 | IL2 | Interleukin-2 |
29 | P07333 | CSF1R | Macrophage colony-stimulating factor 1 receptor |