Fig. 7
From: The potential effect and mechanism of Saikosaponin A against gastric cancer
SSA inhibited apoptosis of MKN-28 cells by regulating the PI3K/AKT/mTOR pathway. a The protein expression levels of PI3K, p-PI3K, AKT, p-AKT, mTOR and p-mTOR in MKN-28 cells after SSA treatment. b The relative protein expression of p-PI3K/PI3K, p-AKT/AKT and p-mTOR/mTOR in MKN-28 cells after SSA treatment. c The protein expression levels of Bax, Bcl-2, Caspase-3, and Cleaved Caspase-3 in MKN-28 cells after SSA treatment. d The relative protein expression of Cleaved Caspase-3, Caspase-3, Bax and Bcl-2 was normalized to β-actin in MKN-28 cells after SSA treatment. e The protein expression levels of PI3K, p-PI3K, AKT, p-AKT, mTOR, p-mTOR, Bax and Bcl-2 in the rescue experiment. f The relative protein expression of p-PI3K/PI3K, p-AKT/AKT, p-mTOR/mTOR, Bax and Bcl-2 in the rescue experiment. Data are presented as the mean ± SD (n = 3), *P < 0.05, **P < 0.01, ***P < 0.001 compared to the control group. The Western blots have been cropped