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Fig. 1 | BMC Complementary Medicine and Therapies

Fig. 1

From: Lentinula Edodes Mycelia extract regulates the function of antigen-presenting cells to activate immune cells and prevent tumor-induced deterioration of immune function

Fig. 1

L.E.M. extract directly activates BMDCs. BMDCs were stimulated by either solvent, 0.01, 0.1, 1, 10, 100, or 200 µg/mL L.E.M. extract, or 10 ng/mL LPS (a positive control). After 12 h of incubation, the expression levels of (a) MHC-I, MHC-II, CD80, CD86 and CD40 were analyzed by flow cytometry (N = 3 per group). The median value is shown in the figure. The data are representative of two independent experiments and were statistically analyzed by one-way ANOVA (*, p < 0.05, compared to vehicle; **, p < 0.01, compared to vehicle; N.S., not significant, compared to vehicle). (b) ELISA measurement of IL-12p70 production in the culture supernatant (N = 3 per group). The median value is shown in the figure. The data are representative of two independent experiments and were statistically analyzed by one-way ANOVA (*, p < 0.05; **, p < 0.01; N.S., not significant)

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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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