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Table 1 The characteristics of included studies

From: Effects of acupuncture on mental health of migraine patients: a systematic review and meta-analysis

Study

Country

Outcome measures

Experimental treatment

Control treatment

Sample size (female/male) (E/C)

Age(y)

[mean(SD)]

(E/C)

Duration(M)

Rescue

medication

Adverse events(E/C)

Diener2006 [28]

Germany

Verum acupuncture

sham acupuncture

247/43 /257/60

37.1(10.5)

/38.3(10.4)

6.5

Beta blockers,fl unarizine,or valproic acid

5/5

Ferro2012 [29]

Brazil

acupuncture

Tanacetum

22/23

38.2(7.4)

/37.3(8.6)

2.5

-

-

Guan2018 [36]

China

Acupuncture

Flunarizine hydrochloride

41/24

/47/18

45.9(10.3)

/46.4(10.2)

3

-

-

Li 2012 [37]

China

acupuncture

sham acupuncture

100/21

/103/15

37.1(11.7)

/37.5(12.1)

4

ibuprofen

9()

/8(⑩)

Li 2017 [38]

China

Verum acupuncture

sham acupuncture

9/2

/9/2

21.73(1.98)

/21.18(1.12)

1

ibuprofen

-

Wang2011 [30]

China

verum acupuncture

flunarizine

59/11

/60/10

39.2(10.9)

/39.2(10.9)

4

 

5()

/7(⑪⑫)

WU2011 [39]

China

Acupuncture

Flunarizine hydrochloride

21/9

/19/11

39.6(9.7)

/39.1(10.2)

1

ibuprofen

-

Xiao2018 [40]

China

Electric acupuncture

Diclofenac sodium enteric-coated

19/11

/16/14

30.8(11.2)

/35.9(9.6)

0.3

-

-

Xu2020 [32]

China

Manual acupuncture

sham acupuncture

47/13

/50/10

36.3(12.0)

/36.0(10.9)

5

Diclofenac sodium enteric coated tablets

5/0

Yang2011 [31]

China Taiwan

Acupuncture

topiramate

30/3

/29/4

47.6(7.4)

/48.1(6.4)

3

 

2()

/22(⑪⑬⑭⑮⑯⑰)

Zhang2021 [41]

China

Acupuncture

Shame acupuncture

24

/20

33.04(6.43)

/35.3(9.43)

3

  

Zhao2017 [42]

China

truth acupuncture

sham acupuncture

65/18

/63/17

36.4(14.2)

/39.1(14.6)

6

ibuprofen

5(⑩)/2()

Zhuang2017 [43]

China

Manual acupuncture

Carbamazepine tablets

27/18

/26/19

37.5(4.7)

/37.8(4.3)

1

-

-

  1. Outcome measures: Zung Self-Rated Anxiety Scale (SAS); Zung Self-rating Depression Scale (SDS); Short Form 36 Mental Health; visual Analog Scale scores (VAS); Migraine-Specific Quality of Life Questionnaire Emotional Functioning Subscale (MSQ)
  2. Adverse events:
  3. Experimental: sedation; local pain; Subcutaneous hemorrhage; subcutaneous hematoma; leg weakness; subcutaneous ecchymosis; discomfort; fatigue; local paresthesia; ⑩a tingling sensation
  4. Control: drowsiness; weight gain; depression; nausea; constipation; abdominal pain; drowsiness; itching; subcutaneous hemorrhage; ⑩subcutaneous hematomash; ⑪fatigue; ⑫ faintness; ⑬paresthesia; ⑭difficulty with memory; ⑮dyspepsia; ⑯dizziness; ⑰somnolence