Table 2 Molecular mass determination and amino acid sequence prediction and In silico prediction results for binding energy and hydrophobicity of peptides derived from green brasil
From: Potential antihypertensive activity of novel peptides from green basil leaves
Sequences | Molecular mass (Da) | Binding energy with ACE (kJ/mol) | Hydro-phobicity at pH 6.8 | IC50 (µM) |
|---|---|---|---|---|
ACE inhibition | ||||
Tyr-Ser-Phe | 416.182 | -5.6 | 51.67 | 44.23 |
Glu-Gly-Ser-Gly-Lys-Gly-Val-Arg | 789.422 | 10.02 | 0.38 | 87.24 |
Asp-Leu-Ser-Ser-Ala-Pro | 589.283 | -7.13 | 5 | 4.75 |
Leu-Asp-Ser-Lys-His-Glu-Ala-Pro | 896.448 | 11.03 | -1.38 | 120.53 |
His-Cys-Gly-Asp-Gly-Asp-Ala-Pro-Tyr | 934.337 | 10.17 | 0.56 | 103.05 |
His-Val-Leu-Ser-Ala | 526.299 | -5.3 | 44 | 10.02 |
Pro-Thr-Thr-Lys-Thr-Asn-Val-Pro-Pro-His-Phe | 1238.653 | 203.78 | 1.64 | 119.45 |
Asp-Ser-Val-Ser-Ala-Ser-Pro | 662.3 | -3.52 | 0.14 | 117.04 |
Glu-Gly-Ser-Gly-Lys-Gly-Val-Arg | 789.422 | 10.02 | 0.38 | 87.24 |
Captopril | Â | -5.91 | - | 0.00197 |
BHA | Â | Â | Â | ND |