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Fig. 7 | BMC Complementary Medicine and Therapies

Fig. 7

From: Cardioprotective effects of Schisantherin A against isoproterenol-induced acute myocardial infarction through amelioration of oxidative stress and inflammation via modulation of PI3K-AKT/Nrf2/ARE and TLR4/MAPK/NF-κB pathways in rats

Fig. 7

Immunofluorescent results of myocardial (A) NF-κΒ p65 and immunohistochemical staining (B) P38 MAPK; (C) Fluorescence intensity (red color) of NF-κΒ p65 and (D) p38 MAPK (% of brown staining). C: Control rats; MI: Isoproterenol (ISO) induced myocardial infarction (MI) in rats; 5 SCA: Treatment of ISO-induced rats with 5 mg SCA/ kg body weight; 10 SCA: Treatment of ISO-induced rats with 10 mg SCA/ kg body weight. The data is presented as mean ± SD (n = 10). Statistical analysis was performed using One-Way ANOVA followed by Tukey’s post hoc analysis to compare differences between groups. Mean values with different superscripts indicate significant differences at a significance level of p < 0.05. The black and white arrow indicates the protein expression specifically in cardiomyocytes. (Scale bar = 50 μm; magnification, x400)

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