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Fig. 6 | BMC Complementary Medicine and Therapies

Fig. 6

From: Cardioprotective effects of Schisantherin A against isoproterenol-induced acute myocardial infarction through amelioration of oxidative stress and inflammation via modulation of PI3K-AKT/Nrf2/ARE and TLR4/MAPK/NF-κB pathways in rats

Fig. 6

Effect of SCA treatment on ISO-induced changes in TLR4/MAPK/NF-kB signaling in cardiac tissue of rats. Relative mRNA expression of (A): Tlr4; (C): IKKβ;(D): ERK; (E): JNK; (F): P38; ELISA reading for (B) NF-kB-p65 levels; C: Control rats; MI: Isoproterenol (ISO) induced myocardial infarction (MI) in rats; 5 SCA: Treatment of ISO-induced rats with 5 mg SCA/kg body weight; 10 SCA: Treatment of ISO-induced rats with 10 mg SCA/ kg body weight. Data are Mean ± SEM (n = 10). *p < 0.05 versus control, and ^p < 0.05 versus ISO. The data is presented as mean ± SD (n = 10). Statistical analysis was performed using One-Way ANOVA followed by Tukey’s post hoc analysis to compare differences between groups. Mean values with different superscripts indicate significant differences at a significance level of p < 0.05

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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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