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Fig. 5 | BMC Complementary Medicine and Therapies

Fig. 5

From: Cardioprotective effects of Schisantherin A against isoproterenol-induced acute myocardial infarction through amelioration of oxidative stress and inflammation via modulation of PI3K-AKT/Nrf2/ARE and TLR4/MAPK/NF-κB pathways in rats

Fig. 5

Immunohistochemical staining for myocardial (A) Nrf2 and (B) Keap 1 distribution. (C) Nrf2 and (D) Keap 1 brown staining indicate the cells with positive staining. C: Control rats; MI: Isoproterenol (ISO) induced myocardial infarction (MI) in rats; 5 SCA: Treatment of ISO-induced rats with 5 mg SCA/ kg body weight; 10 SCA: Treatment of ISO-induced rats with 10 mg SCA/ kg body weight. The data is presented as mean ± SD (n = 10). Statistical analysis was performed using One-Way ANOVA followed by Tukey’s post hoc analysis to compare differences between groups. Mean values with different superscripts indicate significant differences at a significance level of p < 0.05. The black arrow indicates the protein expression specifically in cardiomyocytes. (Scale bar = 50 μm; magnification, x400)

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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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