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Fig. 4 | BMC Complementary Medicine and Therapies

Fig. 4

From: Cardioprotective effects of Schisantherin A against isoproterenol-induced acute myocardial infarction through amelioration of oxidative stress and inflammation via modulation of PI3K-AKT/Nrf2/ARE and TLR4/MAPK/NF-κB pathways in rats

Fig. 4

Effect of SCA treatment on ISO-induced changes in PI3K/Akt/Nrf2/ARE signaling in cardiac tissue of rats. Relative mRNA expression of (A): PI3K; (B): Akt; (C): Nrf2; (D): Keap1; (E): Nqo1;(F): Ho-1. C: Control rats; MI: Isoproterenol (ISO) induced myocardial infarction (MI) in rats; 5 SCA: Treatment of ISO-induced rats with 5 mg SCA/ kg body weight; 10 SCA: Treatment of ISO-induced rats with 10 mg SCA/ kg body weight. The data is presented as mean ± SD (n = 10). Statistical analysis was performed using One-Way ANOVA followed by Tukey’s post hoc analysis to compare differences between groups. Mean values with different superscripts indicate significant differences at a significance level of p < 0.05

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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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