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Fig. 3 | BMC Complementary Medicine and Therapies

Fig. 3

From: Cardioprotective effects of Schisantherin A against isoproterenol-induced acute myocardial infarction through amelioration of oxidative stress and inflammation via modulation of PI3K-AKT/Nrf2/ARE and TLR4/MAPK/NF-κB pathways in rats

Fig. 3

Effect of SCA treatment on ISO-induced changes in rats’ cardiac oxidative stress and antioxidant defense markers. (A): Malondialdehyde (MDA); (B): Nitric oxide (NO) (C): superoxide dismutase (SOD); (D): Catalase (CAT); (E): Glutathione peroxidase (GPx); (F): Glutathione (GSH). C: Control rats; MI: Isoproterenol (ISO) induced myocardial infarction (MI) in rats; 5 SCA: Treatment of ISO-induced rats with 5 mg SCA/ kg body weight; 10 SCA: Treatment of ISO-induced rats with 10 mg SCA/ kg body weight. The data is presented as mean ± SD (n = 10). Statistical analysis was performed using One-Way ANOVA followed by Tukey’s post hoc analysis to compare differences between groups. Mean values with different superscripts indicate significant differences at a significance level of p < 0.05

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