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Fig. 1 | BMC Complementary Medicine and Therapies

Fig. 1

From: Cardioprotective effects of Schisantherin A against isoproterenol-induced acute myocardial infarction through amelioration of oxidative stress and inflammation via modulation of PI3K-AKT/Nrf2/ARE and TLR4/MAPK/NF-κB pathways in rats

Fig. 1

(A): Schematic diagram of experimental design. Effect of SCA treatment on (B): Myocardial infarct size (C): Heart-to-body weight ratio in ISO-injected rats. (D): The myocardial infarct size was assessed through a histological TTC staining assay. The myocardial infarct area is indicated by the black arrow. C: Control rats; MI: Isoproterenol (ISO) induced myocardial infarction (MI) in rats; 5 SCA: Treatment of ISO-induced rats with 5 mg SCA/ kg body weight; 10 SCA: Treatment of ISO-induced rats with 10 mg SCA/ kg body weight. The data is presented as mean ± SD (n = 10). Statistical analysis was performed using One-Way ANOVA followed by Tukey’s post hoc analysis to compare differences between groups. Mean values with different superscripts indicate significant differences at a significance level of p < 0.05. S.C: Subcutaneous; ISO: isoproterenol

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