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Table 4 Influence of BBE on serum and urine samples collected from in experimental rats

From: Phytochemistry, antioxidant, anticancer, and acute toxicity of traditional medicinal food Biarum bovei (Kardeh)

Parameters

G1

G2

G3

Weight (g)

248 ± 14.8

271 ± 21.5

278 ± 23.7

Feed intake (g)

18 ± 4.3

19 ± 3.9

20 ± 5.3

Water intake (ml)

25 ± 6.3

30 ± 4.3

32 ± 3.5

Urine volume (ml)

10.6 ± 4.2

12.6 ± 3.3

13.6 ± 4.4

Urine Creatinine (mg/dl)

52.5 ± 2.2

55.3 ± 3.5

55.7 ± 3.1

Serum Creatinine (mg/dl)

0.6 ± 0.03

1.2 ± 0.08

0.7 ± 0.04

Serum BUN (mg/dl)

47.2 ± 3.1

49.1 ± 3.4

48.3 ± 3.6

SOD(U/mg)

181.3 ± 8.3

134.2 ± 9.2

152.2 ± 5.8

MDA(nmol/mg)

2.3 ± 0.7

2.9 ± 0.8

2.8 ± 0.8

GSH-Px(U/mg)

3.5 ± 1.3

2.1 ± 0.5

2.2 ± 0.7

CK (U/l)

187.4 ± 10.6

422.3 ± 12.5

385.2 ± 11.7

  1. Mean value ± SEM. Values indicated by different superscripts within the same column are different according to the Tukey’s honestly significant difference test at 5% significance level
  2. Abbreviation: BUN blood urea nitrogen, SOD superoxide dismutase, MDA malondialdehyde, GSH-Px glutathione peroxidase, CK creatine kinase. G1, Rats fed on diet with no supplementation; G2, Rats treated with 2000 mg/kg of B. bovei leaves; G3, Rats fed on diet with oral supplementation of 2000 mg/kg of B. bovei corms
  3. *Different letters within the same row mean significant at P < 0.05)