Skip to main content

Table 1 Descriptive statistics of diabetic rats in randomized groups

From: Shenkang protects renal function in diabetic rats by preserving nephrin expression

 

Control

 

Diabetic Nephropathy

 

Shenkang

 

Valsartan

 

Group difference

 

N

Mean

SD

 

N

Mean

SD

 

N

Mean

SD

 

N

Mean

SD

 

Pvalue

Pairwise difference

Body Measure

                  

KW/BW (%)

15

0.41

0.12

 

15

0.67

0.12

 

15

0.52

0.08

 

15

0.54

0.14

 

< 0.01

NC-DN, NC-V, DN-SK, DN-V

Urine measures

                  

Urinary protein (mg/L)

15

647.67

375.52

 

15

852.27

585.58

 

15

710.6

392.24

 

15

1103

582.72

 

0.08

 

Urinary albumin (mg/L)

15

15.03

4.77

 

15

24.78

9.83

 

15

19.13

6.67

 

15

15.03

6.03

 

< 0.01

NC-DN, DN-V

Urine urea nitrogen (mmol/L)

15

436.27

212.65

 

15

457.17

212.4

 

15

435.4

213.89

 

15

389.5

108.89

 

0.96

 

Urine creatinine (µmol/L)

15

4327.4

1915.04

 

15

3367.3

1290.13

 

15

3765.2

1057.02

 

15

2747.35

887.8

 

0.02

NC-V

ACR (ug/mg)

15

33.48

11.86

 

15

68.51

26.28

 

15

45.62

12.47

 

15

50.18

15.69

 

< 0.01

NC-DN, NC-V, DN-SK, DN-V

Blood measures

                  

CHO (mmol/L)

15

1.62

0.42

 

15

1.87

0.42

 

15

1.83

0.39

 

15

1.53

0.23

 

0.02

DN-V

TG (mmol/L)

15

0.58

0.22

 

15

0.82

0.34

 

15

0.99

0.25

 

15

0.9

0.61

 

< 0.01

NC-SK

LDL (mmol/L)

15

0.41

0.1

 

15

0.54

0.17

 

15

0.57

0.16

 

15

0.45

0.13

 

0.01

NC-SK

BUN (mmol/L)

15

10.19

3.4

 

15

18.47

6.13

 

15

14.11

4.45

 

15

18.53

6.84

 

< 0.01

NC-DN, NC-SK, NC-V

Serum creatinine (µmol/L)

15

135.4

11.79

 

15

143.67

24.84

 

15

111.87

11.51

 

15

137.47

17.49

 

< 0.01

NC-SK, DN-SK, V-SK

  1. Notes. KW/BW = kidney weight/body weight, ACR = albumin/creatinine ratio, CHO = Total cholesterol, TG = triglyceride, LDL=
  2. Low-density lipoprotein, BUN = blood urea nitrogen, SD = standard deviation. Differences among groups were tested using analysis of variance (ANOVA) given the data is normally distributed (KW/BW, LDL) and using Kruskal–Wallis test by ranks given the data is not normally distributed (urinary protein, urinary albumin, urine urea nitrogen, urine creatinine, ACR, CHO, TG). Post hoc pairwise comparisons were conducted by Tukey HSD test given the data is normally distributed (KW/BW, LDL) and Pairwise Wilcoxon Rank Sum test given the data is not normally distributed (urinary protein, urinary albumin, urine urea nitrogen, urine creatinine, ACR, CHO, TG).