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Table 1 Characteristics of the included reviews

From: Management of post-traumatic stress disorder symptoms by yoga: an overview

Review

Study design

N of primary studies

(N of yoga studies)

N Sexe ratio (% women) Age

Population (N RCTs)

Yoga interventions (N RCTs)

 

Duration

Frequency

N of sessions

Time of session

PTSD

outcomes (N)

Others (N)

Control group

Specific results of yoga

Other interventions (N RCTs)

Mains results and conclusions

Bisson et al

2020 UK[23]

SR + MA

30

(5)

1828 [15–191]

n.r

n.r

Veterans (7)

Military (7)

Civilians with PTSD (14)

Children a (2)

TiY (1)

KrY (2)

SKY (2)

 

n.r

n.r

WLC/TAU (4)

TAU (1)

Low QOE for yoga benefits on PTSD symptoms

     

MBSR (5)

MR (3)

TMS (3)

Acupuncture (2)

Neurofeedback (2)

Saikokeishikankyoto

(1)

Somatic experiencing (1)

Other (8)

 

n.r

n.r

WLC/TAU (10)

WLC (4)

PCT (4)

Sham TMS (3)

WLC/CBT-TF (2)

Paroxetine (1)

Psychoeducation (1)

Emerging evidence for 6 non- pharmacological and non-psychological interventions for the treatment of PTSD in adults (yoga, acupuncture, neurofeedback, somatic experiencing, saikokeishikankyoto and TMS)

All interventions excepted yoga have low QOE

Björkman et al

2021

Sweden [24]

SR + MA

10

(5)

605 [38–338]

57%

Mean ageb: 45.5 yo

Veterans (2)

Veterans and active-duty personnel (1)

Veterans and civilians’ women (1)

Civilians with PTSD (4)

Online hatha yoga (1)

KY (1)

TSY with KrY (1)

KrY (1)

TIY (1)

 

8—12 weeks

Weekly – 2/week

10—20 sessions

1—1.5 h

PCL (2)

CAPS (2)

ies (1)

Depression, anxiety, sleep behavior, dissociative symptoms

WLC / TAU (1)

WLC (1)

Attention placebo + TAU (1)

Attention placebo (1)

Assessment only control (1)

No significant differences between low- or high-intensity activities (yoga versus other exercises)

     

Aerobic and resistance training (1)

Aerobic and anaerobic (2)

Resistance training (2)

 

3—20 weeks

Weekly—3/week

9—26 sessions

30 min—1 h

PCL (2)

CAPS (1)

HTQ (1)

PDS (1)

Depression, anxiety, QOL, sleep behaviour, substance abuse

TAU (2)

WLC (1)

WLC / TAU (1)

Attention placebo (1)

Positive significant effect of exercise on PTSD symptom severity compared to non-active treatment; high heterogeneity in the results

Significant positive effects of exercise for depression, sleep, reduced substance abuse, and increased QOL. No significant result for anxiety

Exercise can be included as a part of PTSD treatment

Cramer et al. 2018

Germany

[25]

SR + MA

7

(7)

385 [21–100] 46.2%

[28.7–58] yo

Veterans (3)

Active military and veterans (1) Civilians with PTSD (3)

SKY (2)

KY (1)

KRY (2)

SatY (1)

TIY (1)

 

7 days – 6 months

Monthly – daily

7—32 sessions

1 h – 4.4 h

PCL (7)

CAPS (3) TLEQ (1)

IES (1)

DES (1)

DTS (1)

Retention

Safety

WLC (4) Attention control intervention (2)

No treatment (1)

Low QOE in favor of yoga compared to no treatment

Very low QOE for no differences of yoga compared to attention control interventions

Very low QOE for no difference of retention between yoga and both types of control

1 adverse event

Gallegos et al. 2017 United states

[26]

SR + MA

19

(4)

1173

n.r

n.r

Veterans (14) Civilians with PTSD (5)

KrY (1)

TIY (1)

KY (1)

MBX (1)

 

6 – 10 weeks

Weekly—2/week

8—16 sessions

1 h – 1.5 h

CAPS (7)

PCL (6)

PVSDS (1)

IES (1)

WLC (2)

SWHE (1)

ACG (1)

Marginally significant effects of yoga due to low statistical power and heterogeneity in treatments effects

     

Mindfulness (9): MBSR (8), MBB (1)

Other meditationsc (6) including SKY (2) d

Combination of mindfulness and meditative practices (1)

 

5 days – 12 weeks 2/week – Daily

6—22 sessions

20 min—6 h

PCL (3)

CAPS (1)

TAU (3) WLC (3)

PCGT (3) Individual psychotherapy (1) Prolonged Exposure (1)

PTSD education group (1)

Sitting quietly (1)

Sleep hygiene (1)

Telehealth psychoeducation (1)

Overall small to moderate ES in favor of meditation and yoga interventions

No differences between intervention types, study population, outcome measures, or control condition

Meditation and yoga are promising complementary approaches and can be provided as second-line treatment in PTSD

Hilton et al. 2017

USA

[27]

SR + MA

10

(3)

643 [28–146]

32.9% [41,–59] yo

Military (6)

Civilians with PTSD (4)

KY (1)

KrY (1)

TIHY (1)

 

8 – 12 weeks

Monthly – weekly

8—14 sessions

1 h – 1.5 h

PCL (2)

CAPS (1)

Anxiety

Depression

Adverse events

WLC + TAU (2) TAU, waitlist, women’s health education (1)

Yoga has significant effects on PTSD symptoms and on depression

Metaregression: no systematic differences among intervention types on PTSD outcomes (MR/yoga/MBSR)

     

MBSR (5)

MR (2)

 

4 – 8 weeks

Weekly – 2/week

6—9 sessions

26 min – 2.5 h

CAPS (5)

PCL (7)

Anxiety Depression QOL Adverse events

TAU (3)

WLC + TAU (2)

PCGT (1)

Psycho-education telehealth (1)

Low QOE for significant decrease in PTSD symptoms of all adjunctive interventions compared to any control

No adverse events and no significant results for anxiety

Kysar-Moon et al

2021

USA

[28]

SR + MA

3

(3)

152 [38–64]

100%

[18–70] yo, mean age 41.7 yo

Veterans and civilian women (1)

Civilians with PTSD (2)

TSY (1)

TIY (1) Trauma-focused yoga (1)

 

6—12 weeks Weekly – 2/week

10—12 sessions

n.r

CAPS (1)

PCL (1)

n.r (1)

Depression

WLC (1)

SWHE (1)

ACG (1)

No significant effects on PTSD symptoms

No significant effects on depression symptoms

Rosenbaum et al

2015

Australia

[3]

SR + MA

4

(2)

200 [17–81]

n.r

[34–52] yo

Civilian with PTSD (3)

Veteran (1)

KrY (1)

TIY (1)

 

6—12 weeks

Weekly – 2/week

10—12 sessions

1 h—1.15 h

PSS-I (1)

CAPS (1)

Depression

Health education (1)

No treatment (1)

No specific result for yoga intervention

     

Combined aerobic and resistance-based intervention (1)

Aerobic intervention (stationary cycling) (1)

 

n.r

n.r

12 sessions

n.r

PSS-I (1)

PCL (1)

Depression

Cardiovascular risk

TAU (2)

Physical activity significantly reduced PTSD and depressive symptoms compared to control Insufficient datas for anthropometric measures

Zhu et al.,

2022

China

[29]

SR + MA

16

(9)

871 [21–116] 45.5%

[18–65] y.o

Adults with PTSD

SKY (2)

KrY (2)

KY (1)

SatY (1)

TiY (1)

Hatha yoga (1)

Online yoga (1)

 

1—16 weeks

Weekly—daily

5 – 32 sessions

1 h—4.4 h

PCL (7)

CAPS (3)

IES (1)

Anxiety

Depression

Regular daily life (4)

No treatment (2)

TAU (1)

Mandatory ordinary assistance protocol (1)

Toning exercise (1)

No specific result for yoga intervention

MBSR (4)

MBX (1)

Brief mindfulness training (1)

Integrative exercise (1)

 

4—8 weeks

Weekly—daily

4—64 sessions

1—2.5 h

PCL (5)

CAPS (1)

BRUMS (1)

Anxiety

Depression

TAU (3)

Regular daily life (2)

WLC (1)

PCGT (1)

Mind–body exercises had significant effects on PTSD symptoms, depression, and anxiety in patients with PTSD

Liu et al

2018

USA

[30]

SR

13

(3)

953 [29–226]

n.r (yoga = 100%)

n.r

Veterans (5)Veteran civilian adult women (2)Civilians including (6) adults, nurse, refugees, women with chronic PTSD, childrena

KrY (2)

TIY (1)

 

10 weeksb

Weeklyb

10—20 sessions

1 h -1.15 h

CAPS (2)

PCL (1)

DTS (1)

DES (1)

ACG (2)

Women’s health education classes (1)

2/3 RCTs found significant difference after yoga intervention

None of the studies provided power analysis calculations for primary outcomes

    

Mindfulness/ meditation (7)

Spiritually based intervention (1)

Acupuncture (1)

Relaxation training (1)

 

8 weeks – 12 weeks

Weekly—2/week

1 to 16 sessions

20 min to 7 h

PCL (7)

CAPS (4)

PTSD SSS (1)

PSS-SR (1)

Researcher-devised self-report assessment of PTSD (1)

Biological levels (1)

TAU (2)

DI (1)

WLC (1)

No treatment (2)

Psychoeducation (1)

PCGT (1)

CBT + WLC (1)

Exposure + EMDR (1)

Integrative body-mind-spirits interventions have positive effects for treating PTSD

Niles et al

2018

USA

[31]

SR

22

(6)

1258 [21–146]

46.4% Mean ageb = 44,9

Veterans (8) Active-duty personnel or civilian and veterans (2)

Civilians with PTSD (12)

SKY (2)

KrY (2)

KY (1)

TIHY (1)

 

7 days—6 months

2/week—daily

7—20 sessions

1 h – 4.4 h

CAPS (3)

PCL (5)

ies (1)

DTS (1)

17 scales for additional measures

WLC (2)

OF (1)

ACG (2)

SWHE (1)

All studies have large within-group effects and 4/6 RCTs significant moderate to large effect size between-group

Acceptable and feasible intervention

    

Mindfulness (9): MBSR (4), MR (2), MBX (1), telehealth mindfulness (1), PCBMT (1)

Relaxation (7)

 

4 – 16 weeks

Weekly – 2/week

3—16 sessions

20 min—7 h

CAPS (10), PCL (10)

IES (3)

SI-PTSD (1)

PTS-T (1) PTSDSS (2) PSS-SR (1)

17 scales for additional measures

WLC (3)

TAU (3)

PCGT (2)

ACG (2)

DI (1)

EMDR (1)

CBT (1)

Telehealth psychoeducation (1)

Others (4)

Mind–body therapies have encouraging evidence but still have methodologic weaknesses

Not enough studies have evaluated the secondary outcomes

Sciarrino et al. 2017

USA

[32]

SR

7

(7)

391 [22–100]

n.r

n.r

Military (2)

Veterans and civilian women (1)

Civilians with PTSD (4)

SKY (1)

KrY (1)

KY (1)

SatY (1)

TSY (1)

Hatha yoga (1)

MBX + yoga postures (1)

 

5 days – 16 weeks

Monthly – daily

10—32 sessions

1 h – 4.4 h

PCL (4)

CAPS (2)

PDS (1)

WLC (3)

No treatment (2)

SWHE (1)

Demobilization program (1)

5/7 RCTs found significant results in favor of yoga compared to control

  1. aChildren’s samples did not concern yoga interventions, b Incomplete data, c Includes a three arms study, d Yoga is considered as meditation here, CI Confidence intervals, ES Effect-size, MA Meta-analysis, MS Multiple sclerosis; n.r: not reported, QOE Quality of evidence, QOL Quality of life, SR Systematic review, SMD standardised mean difference
  2. PTSD SCALES: BRUMS Brunel mood scale rating, CAPS Clinician administered PTSD scale, DES Dissociative experience scale, DTS Davidson trauma scale, HTQ Harvard trauma questionnaire, IES Impact of events scale, PCL PTSD checklist (including military, civilian, and 17), PDS Post-traumatic stress diagnostic scale, PVSDS PTSD checklist, PSS-I PTSD symptom scale-Interview, PSS-SR Post- traumatic symptom scale-self report. PTS-T Posttraumatic stress-total on the detailed assessment of posttraumatic states, PTSDSS PTSD symptom severity scale, part of the posttraumatic stress diagnostic scale, SI-PTSD PTSD structured interview, TLEQ Trauma life events questionnaire
  3. INTERVENTIONS: KrY kripalu yoga, KY Kundalini yoga, MBB Mind–body bridging, MBSR Mindfulness-based stress reduction, MBX Mindfulness-based stretching and deep breathing exercise, MR Mantram repetition, PCBMT Primary care brief mindfulness training, SatY Satvananda yoga, SKY Sudarshan kriya yoga, TI(H)Y trauma-informed (hatha) yoga, TMS Transcranial magnetic stimulation, TSY Trauma-sensitive yoga
  4. CONTROL GROUPS: ACG Assessment control group, CBT-TF Cognitive-behavioural therapy with a trauma focus, CBT Cognitive behavioral therapy, DI Delayed-intervention control group, EMDR Eye movement desensitization and reprocessing, PC(G)T Present-centered (group) therapy, SWHE Supportive women’s health education, TAU Treatment as usual, WLC Wait-list control