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Table 3 Histological types of tumors obtained following DMBA exposition

From: Comparative anticancer effects of Annona muricata Linn (Annonaceae) leaves and fruits on DMBA-induced breast cancer in female rats

 

Histological type

SBR grade

Lymphocyte infiltration (%)

Nécrosis

& comedonecrosis

DMBA

Cribriform ductal carcinoma

III

< 5%

30%

Tamox

Fibrosarcoma

I

0%

0%

AML

Cribriform ductal carcinoma

II

30%

20%

AMF-3 day

Cribriform ductal carcinoma

II

0%

20%

AMF_ Daily

Cribriform ductal carcinoma

II

20%

0%

  1. Normal (NOR) and negative control (DMBA) groups received distilled water (vehicle); Tamox + DMBA = rats serving as positive control, treated with tamoxifen at 3.3 mg/kg BW; AML + DMBA = rats treated with the ethanolic extract of A. muricata leaves at 200 mg/kg BW; AMF = rats treated with A. muricata pulp fruit aqueous extract at 200 mg/kg BW for 2 different frequencies (3 times/week and every day)
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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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