Fig. 2

Effects of A. muricata Linn leaves extract and juices on tumor morphology (A) tumor volume (B) and CA15-3 level (C). Normal (NOR) and negative control (DMBA) groups received the vehicle (distilled water); Tamox + DMBA = positive control group, treated with tamoxifen at 3.3 mg/kg BW; AMF + DMBA = rats treated with the ethanolic extract of A. muricata Linn leaves at 200 mg/kg BW. AMF = rats treated with A. muricata Linn pulp fruit aqueous extract at 200 mg/kg BW at 2 different frequencies (3 times/week and every day). Significance compared to the DMBA group: * p < 0.05; ** p < 0.01 and *** p < 0.001. Significance compared to the NOR group: ##p < 0.01 and ### p < 0.001 compared to the NOR group (n = 8)