Table 1 Molecular docking simulations results for the compounds and Caspase-8, NRF2, SOD, TNF-α and NF-κB receptors
Compounds | PDB ID: 1QTN | PDB ID: 4L7B | PDB ID: 5YTO | PDB ID: 2AZ5 | PDB ID: 1NFK |
|---|---|---|---|---|---|
Caspase-8 | NRF2 | SOD | TNF-α | NF-κB | |
1 | -7.9 | -8.2 | -8.1 | -7.6 | -7.3 |
2 | -8.1 | -8.1 | -8.5 | -7.8 | -7.2 |
3 | -8.3 | -9.4 | -9.2 | -7.7 | -7.8 |
4 | -8.6 | -8.7 | -8.8 | -8.1 | -7.3 |
5 | -8.3 | -8.9 | -8.3 | -8.4 | -7.6 |
6 | -9.3 | -8.4 | -9.6 | -8.0 | -7.5 |