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Fig. 6 | BMC Complementary Medicine and Therapies

Fig. 6

From: Gallic acid and metformin co-administration reduce oxidative stress, apoptosis and inflammation via Fas/caspase-3 and NF-κB signaling pathways in thioacetamide-induced acute hepatic encephalopathy in rats

Fig. 6

Effect of TAA and/or (GA and/or Met) on histopathological examination of brains (H&E.100 μm). A-A photomicrograph of a section in the cerebrum of a control animal, displaying normal architecture with intact blood vessels (bl.v), pyramidal neurons (black arrow), satellite cells (red arrow), and oligodendroglia (blue arrow). B-A photomicrograph of a section in the cerebrum of affected TAA group, displaying bulged neuron (black arrow), neurons shrinkage (blue arrow) and a pyknotic nucleus (red arrow). C-A photomicrograph of a section in the cerebrum of animals treated with TAA and GA, displaying large pyramidal cells without dendrites (black arrow), axons of small pyramidal cells (green arrow), vacuoles in the cerebral cortex with disarrangement of cerebral cells (v), granular cells (red arrow), small pyramidal cells without dendrites (yellow arrow), and numerous micoglial cells (blue arrow). D-A photomicrograph of a section in the cerebrum of animals treated with TAA and Met, displaying pyramidal neuron appear normal, relaxation of waves between neuron (black line), small pyramidal neurons (green arrow), large pyramidal neurons (blue arrow), foamy structure between neurons (grey arrow) and numerous microglial cells (red arrow). E-A photomicrograph of a section in the cerebrum of animals treated with TAA (GA + Met) showed an normal histological structure of the brain. (GA) gallic acid, (Met) metformin, (TAA) thioacetamide

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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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