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Table 3 Cytotoxicity, anti-HAdV-7 activities and selectivity indices of licorice ethyl acetate fractions on Hep-2 cells*

From: Metabolic bioprofiling of different Glycyrrhiza glabra solvent fractions for the identification of anti-adenoviral compounds using LC-HRMS/MS and in-vitro cytopathic assay coupled with chemometry

Fraction #

CC50a(μg/mL)

IC50b(μg/mL)

SIc

1

35.767 ± 1.14

8.216 ± 1.62

4.353335

2

10.144 ± 1.78

8.302 ± 0.83

1.221874

3

18.682 ± 1.67

1.609 ± 1.59

11.61094

4

50.918 ± 2.19

10.824 ± 2

4.704176

5

35.54 ± 0.51

6.647 ± 2.05

5.346773

6

40.82 ± 1

1.431 ± 1.5

28.52551

  1. *Results are expressed as mean ± SD of duplicate measurements
  2. a50% cytotoxic concentration on normal Hep-2 cells
  3. b50% inhibitory concentration on HAdV-7
  4. cselectivity index
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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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