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Table 1 Characteristics of Eligible Guidelines

From: Complementary and alternative medicine mention and recommendations in inflammatory bowel disease guidelines: systematic review and assessment using AGREE II

Guideline

Country

Developer

CAM Category

Guideline Topic

Macaluso et al. 2022 [36]

Italy

Italian Group for the study of

Inflammatory Bowel Disease

None

Pharmacologic management of moderate to severe UC

Raine et al. 2022 [37] & Spinelli et al. 2022 [38]

Austria

European Crohn’s and Colitis Organisation

Probiotics

Medical and surgical treatment of UC

De Simone et al. 2021 [39]

Italy; United States

World Society of Emergency Surgery; American Association for the Surgery of Trauma

None

Emergency management of IBD

Feuerstein et al. 2021 [40]

United States

American Gastroenterological Association

None

Pharmacologic management of moderate to severe luminal and perianal fistulizing CD

Holubar et al. 2021 [41]

United States

American Gastroenterological Association

None

Surgical management of UC

Lodyga et al. 2021 [42]

Poland

Polish Society of Gastroenterology; Polish National Consultant in Gastroenterology

Vitamins and Minerals

Management of CD

Miehlke et al. 2021 [43]

Austria; Sweden

United European

Gastroenterolog; European Microscopic Colitis Group

Vitamins and Minerals

Management of microscopic colitis

Nakase et al. 2021 [44]

Japan

Japanese Society of Gastroenterology

None

Management of IBD

Adamina et al. 2020 [45]

Austria

European Crohn’s and Colitis Organisation

None

Surgical treatment of CD

Feuerstein et al. 2020 [46]

United States

American Gastroenterological Association

None

Management of moderate to severe UC

Levine et al. 2020 [47]

United States

American Gastroenterological Association

Dietary Supplements

Dietary management of IBD

Colombel et al. 2019 [48]

United States

American Gastroenterological Association

Fecal Microbiota Transplantation, Hypnotherapy, Mindfulness, Probiotics

Management of IBD functional gastrointestinal symptoms

Lightner et al. 2020 [49]

United States

American Society of Colon and Rectal Surgeons

None

Surgical management of CD

Shen et al. 2020 [50]

United States*

Global

Interventional Inflammatory Bowel Disease Group

None

Endoscopic treatment of CD

Torres et al. 2020 [51]

Austria

European Crohn’s and Colitis Organisation

None

Pharmacologic treatment of CD

Bonnaud et al. 2019 [52]

France

National Association of the Hepato-gastroenterologists of the National Hospitals

Reflexion Club of the Practices and Groups in Hepato-gastroenterology

Group for the Study of Treatments for Inflammatory Affectations of the Digestive Tube

AFA Crohn-RCH France

None

Management of CD perianal fistulas

Ko et al. 2019 [53]

United States

American Gastroenterological Association

Herbals, Probiotics

Management of mild to moderate UC

Kucharzik et al. 2019 [54]

Germany

German Society for Gastroenterology, Digestive and Metabolic Diseases

Acupuncture, Fecal Microbiota Transplantation, Herbals, Mind-body Medicine, Probiotics

Management of UC

National Institute for Health and Care Excellence (NICE) 2019 [55]

United Kingdom

National Institute for Health and Care Excellence (NICE)

None

Management of UC

Panaccione et al. 2019a [56] & Panaccione et al. 2019b [57]

Canada

Canadian Association of

Gastroenterology

Cannabis, Dietary Supplements, Probiotics

Management of luminal CD

Rubin et al. 2019 [58]

United States

American College of Gastroenterology

Herbals, Probiotics

Management of UC in adults

Sood et al. 2019 [59]

India*

Asian Working Group

Dietary Patterns, Probiotics

Dietary management of IBD

Steinhart et al. 2019 [60]

Canada

Canadian Association of

Gastroenterology

None

Management of perianal fistulizing CD

Teixeira et al. 2019 [61]

Brazil

Brazilian Medical Association

None

Biologicals treatment of UC

Zaltman et al. 2019 [62]

Brazil

Brazilian Medical Association

None

Biologicals treatment of CD

Bemelman et al. 2018 [63]

Austria

European Crohn’s and Colitis Organisation

None

Surgical treatment of CD

Brown et al. 2018 [64]

United Kingdom

Association of Coloproctology of Great Britain and

Ireland

Fecal Microbiota Transplantation, Probiotics

Surgical treatment of IBD

Lichtenstein et al. 2018 [65]

United States

American College of Gastroenterology

Dietary Therapies

Management of CD in adults

Forbes et al. 2017 [66]

Luxembourg

European Society for Clinical Nutrition and Metabolism

Dietary Patterns, Dietary Supplements, Probiotics, Vitamins and Minerals

Nutritional management of IBD

Gionchetti et al. 2017 [67]

Italy

Italian Group for the Study of Inflammatory Bowel Disease

None

Corticosteroid and immunosuppressive treatment of IBD

Nguyen et al. 2017 [68]

United States

American Gastroenterological

Association

Probiotics

Management of CD in post-surgical resection patients

Bernstein et al. 2016 [69]

Canada

World Gastroenterology Organisation

Cannabis, Ispaghula, Probiotics

Management of IBD

Harbord et al. 2016 [70]

Austria

European Crohn’s and Colitis Organisation

Vitamins and Minerals

Management of IBD extraintestinal manifestations

Bressler et al. 2015 [71]

Canada

Canadian Association of Gastroenterology

Fecal Microbiota Transplantation, Probiotics

Management of UC in non-hospitalized patients

Eliadou et al. 2015 [72]

New Zealand

New Zealand Society of

Gastroenterology

Fecal Microbiota Transplantation

Management of refractory UC

Fichera & Zoccali 2015 [73]

United States

Crohn’s & Colitis Foundation of America

Adipose-derived Stem Cells

Surgical treatment of perianal fistulizing CD

Schwartz et al. 2015 [74]

United States

Crohn’s & Colitis Foundation of America

None

Management of perianal fistulizing CD

Strong et al. 2015 [75]

United States

American Society of Colon and Rectal Surgeons

None

Surgical treatment of CD

Gecse et al. 2014 [76]

United States

World Gastroenterology Organization

None

Management of perianal fistulizing CD

Lee et al. 2014 [77]

United Kingdom

British Dietetic Association

Probiotics

Dietary management of CD

Ross et al. 2014 [78]

United States

American Society of Colon and Rectal Surgeons

Probiotics

Surgical treatment of UC

Gomollon et al. 2013 [79]

Spain

Spanish Group of Ulcerative Colitis and Crohn’s

Disease

None

Management of UC

Leung et al. 2013 [80]

China

Hong Kong IBD Society

None

Biological treatment of IBD

Terdiman et al. 2013 [81]

United States

American Gastroenterological Association

None

Thiopurines, methotrexate, and anti-TNF-α treatment of CD

Theede et al. 2013 [82]

Denmark

Danish Society of Gastroenterology and

Hepatology

None

Biologicals treatment of IBD

Ueno et al. 2013 [83]

Japan

Guidelines Project Group of the Research Group of Intractable

Inflammatory Bowel Disease

Dietary patterns

Management of CD

Bitton et al. 2012 [84]

Canada

Canadian Association of Gastroenterology

None

Treatment of severe UC in hospitalized adults

Mowat et al. 2011 [85]

United Kingdom

British Society of Gastroenterology

Dietary patterns, Probiotics, Vitamins and Minerals

Management of IBD in adults

Orlando et al. 2011 [86]

Italy

Italian Society of Gastroenterology; Italian Group for the study

of Inflammatory Bowel Disease

None

Anti-TNF-α treatment of IBD