Effect of acupuncture on episodic memory for amnesia-type mild cognitive impairment: study protocol of a multicenter, randomized, controlled trial

Table 2 Trial processes chart

Study period Item	Enrolment and Baseline	Intervention Period (8 weeks, one time per 4 weeks)				Follow-up phase
Week	-2 to 0	1 to 3	4	5 to 7	8	12
Enrolment
Inclusion criteria	×
Exclusion criteria	×
Informed consent	×
Intervention
TSYZ acupuncture group		×	×	×	×
Sham acupuncture group		×	×	×	×
Blank control group
Outcome measurement
GDS	×
BDI	×
MoCA	×		×		×	×
AVLT	×		×		×	×
TMT	×		×		×	×
DSST	×		×		×	×
SF-36	×		×		×	×
fMRI scan	×				×
EEG	×				×
Safety
Adverse events		×	×	×	×	×
Reasons for dropout and withdrawals		×	×	×	×

TSYZ Tiaoshenyizhi, GDS Global Deterioration Scale, BDI Beck Depression Inventory, MoCA Montreal Cognitive Assessment, AVLT-H Auditory Verbal Learning Test-Huashan version, TMT Trail Making Test, DSST Digit Span Subtest, SF-36 Medical Outcomes Study 36-item short form health survey, EEG Electroencephalogram, fMRI Functional magnetic resonance imaging

ISSN: 2662-7671